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How
Was It Discovered?
The
green-lipped mussel is native to the New Zealand coast
and had been a staple in the diet of the indigenous Maori
culture for hundreds of years. The anti-inflammatory effects
of green-lipped mussel have been studied since the observation
of a lower incidence of arthritis in coastal Maoris compared
with European or inland Maori people.
For
centuries, it has provided an excellent source of protein,
vitamins, minerals and extremely valuable Omega-3 Fatty
Acids.
Following
over 15 years of international scientific research by
independent scientists from the Royal Melbourne Institute
of Technology University, the principal components responsible
for the extracts high potency were isolated.
Stabilizing
the mussel powder was a major break-through. This meant
that its anti-inflammatory activity could be maintained
without the risk of oxidation.
The
difference between the potency of stabilized and unstabilized
mussel powder was born out by Dr. Michael Whitehouse’s
comparative study of the anti-arthritis inflammation activity
of both stabilized and unstabIlized mussel powders in
1997. The study showed dramatic results 90% and 14% respectively,
for the two mussel powders inflammation reduction activity.
What
Is The Science Behind Pernax?
PERNAX
has been the subject of numerous scientific studies, each
demonstrating unique benefits from its pure ingredients.
The unique grouping of Omega 3 fatty acids in PERNAX are
potent inhibitors of the lipoxygenase (5-lipoxygenase)
pathway, which is where leukotrienes are produced, resulting
in the down-regulation of the production of these harmful,
inflammation-causing substances.
Numerous
clinical studies have linked the omega-3s in green lip
mussels to measurable health benefits, including a study
at the University of California which linked these omega-3s
to reduced arthritic symptoms. (See Allerg Immunol (Paris),
Sept. 2000;32(7):272-8).
A 2003
study at the Yonsei Medical Clinic validated the clinical
effectiveness of green lip mussel extract given to patients
with osteoarthritis. (See Allerg Immunol (Paris). June
2003;35(6):212-6.) Additional studies are available upon
request.
Evening
Primrose Oil: Completing the One-Two Punch of PERNAX
Virgin
Evening Primrose Oil is the perfect companion nutrient
in PERNAX’s formula to create a serious fight against
inflammation when combined with its Green-lipped mussel
extract. How? Oil from the seed of the Evening Primrose,
a small yellow wildflower (Oenothera biennis), is rich
in linoleic acid, an essential fatty acid (which, by
definition, means that humans must consume this nutrient
because it is not made by the body). EPO is the richest,
natural source of Gamma-Linolenic Acid, or GLA, containing
about 72% Linoleic acid and 9% GLA. Since it contains
the essential GLA, Evening Primrose Oil is highly valuable
to those who cannot otherwise form enough GLA and, unfortunately,
the body becomes depleted of GLA as we age.
Linoleic
Acid, which acts as an energy source, is what the body
converts to GLA which, in turn, forms other substances
such as prostaglandins. Prostaglandins -- hormone-like
substances found in every cell in the body— are critical
to the body’s overall health maintenance, but need to
be replenished constantly as once they serve their purpose,
they are destroyed. These purposes include lowering blood
pressure, reducing risks of blood clotting, stimulating
the immune system, and regulating brain function.
In
some studies, Evening Primrose Oil has been shown to
increase the desirable anti-inflammatory prostaglandin
E1. In studies in Europe and England, EPO has been shown
to be effective for its pain reduction in association
with arthritis, while additional research has shown
GLA to be beneficial for a number of other conditions
including rheumatoid arthritis, where studies with GLA
show significant improvement in joint stiffness, swelling,
and overall discomfort
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